The European Politics and Institutions Programme covers the EU’s institutional architecture, governance and policymaking to ensure that it can move forward and respond to the challenges of the 21st century democratically and effectively. It also monitors and analyses political developments at the EU level and in the member states, discussing the key questions of how to involve European citizens in the discussions over the Union’s future and how to win their support for European integration. The Programme has a special focus on enlargement policy towards the Western Balkans, questions of EU institutional reform and illiberal trends in European democracies.

The EPC’s Europe’s Political Economy Programme (EPE) focuses on EU economic governance, the single market, and digital, industrial, energy, trade, and economic security policies amid significant geo-economic and technological shifts. In a world of rising geopolitical competition and a fragmenting economy, the EPE has been at the forefront of research on Europe’s competitiveness agenda, the "triple" green, digital and economic security transitions and "wartime economy". The EPE's cross-programme flagship initiative, the Brussels Economic Security Forum, examines EU-US-China dynamics, changing international economic rules and statecraft, as well as related EU policy challenges. As fast-advancing components of economic security, critical emerging technologies in clean tech, semiconductor and AI value chains and quantum are priority areas of focus. Using its convening power and multistakeholder taskforce model, the Programme aims to provide in-depth analysis and actionable recommendations to tackle key policy challenges. The EPE team comprises a diverse group of analysts with backgrounds from government, the private sector, academia, and journalism, bringing a broad range of expertise to its work.